eccrisis
基本解釋
- n. 排泄
專業(yè)釋義
- 排泄
Results: 11C-HupA was of the characteristic that quickly discharge from the blood,which half time was 14.608±1.773min,clearance rate was 0.12±0.009ml/min/kg, metabolism through the liver,kidney was the main eccrisis organ,which was 3.562±0.360%ID/g at 15 min and decreasing graduately,it was 2.547±0.337ID/g in liver at 15 min,Until 60 min the discharging of 11C-HupA was keeping in a relative higher level. Pharmacokinetics of 11C-HupA in the rats corresponded to one-compartment model.
結果;11C-HupA進入大鼠體內具有血液清除快的特點,半衰期為14.608±1.773min,藥物自體內總清除率為0.12±0.009ml/min/kg,經肝膽系統(tǒng)代謝,腎組織是11C-HupA的主要排泄器官,在15min達到高峰,為3.562±0.360%ID/g,之后呈逐漸下降的趨勢,肝臟在15min為2.547±0.337ID/g,60min之前放射性分布維持在較高的水平。