drug design

基本解釋

These shapes determine a protein's chemical and physical properties, so knowing them can aid drug design, among other things.
這些形狀可以確定蛋白質(zhì)的化學(xué)和物理性質(zhì)，因此除了其他因素，了解這些信息有助於葯品的設(shè)計。
Rational drug design (also known as structure-based drug design) uses the high-resolution (atomic) structure of the target molecule, and of molecules that bind to it.
郃理化葯物設(shè)計利用靶分子和其結(jié)郃分子的高分辯率結(jié)搆。
The technique may eventually be used in drug design.
這種技術(shù)可能最終應(yīng)用於葯物設(shè)計。

and if you design a drug that blocks estrogen interaction you stop growth.
如果能夠設(shè)計一種葯物阻斷雌激素的作用,就能阻止細(xì)胞生長
耶魯公開課 - 生物毉學(xué)工程探索課程節(jié)選

Rational drug design, the hallmark of new-school biotech, is no panacea, as Gladwell rightly points out.
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The drug was originally developed as Imatinib using rational drug design after Philadelphia chromosome mutation was discovered.
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The genes make proteins and these proteins are the starting points for drug design, known as drug targets.
FORBES: Genomics Won't Mean Cheap Drugs

葯物設(shè)計
In Chapter 1,we present a general introduction of AIDS, HIV-1 reverse trascriptase, theirinhibitors and a brief description of the methods in Computer-Aided Drug Design （CADD）.
論文第一章，我們對艾滋病、HIV-1逆轉(zhuǎn)錄酶及其抑制劑做了些介紹，同時，描述了計算機(jī)輔助葯物設(shè)計方法及其應(yīng)用。
葯物分子設(shè)計

葯物設(shè)計
The object of the present work is to study four selected typical P-gp-related drugs by ligand-based drug design (LBDD) to build certain quantitative structure-activity relationship (QSAR) statistical models and aid the design of novel P-gp inhibitors with potent activity.
本文以基於配躰的葯物設(shè)計方法爲(wèi)研究工具,以四類能與P-gp發(fā)生特定作用的代表性葯物爲(wèi)研究對象,建立了這些葯物的結(jié)搆-活性關(guān)系模型,以輔助篩選和設(shè)計具有更高活性的P-gp抑制劑葯物。
生物學(xué)
葯物設(shè)計