huntingtin

基本解釋

We concluded that normal huntingtin works as a lifesaving protein for neurons.
我們的結(jié)論是：正常的杭丁頓蛋白是神經(jīng)細(xì)胞裡救命的蛋白質(zhì)。
In contrast, mutant huntingtin does not stimulate the BDNF promoter, resulting in a decrease in BDNF production.
反之，變異的杭丁頓蛋白就未能刺激BDNF的啓動(dòng)子，導(dǎo)致BDNF的産量下降。
In particular, huntingtin appears to activate the “on” switch, or promoter, of the gene that encodes BDNF.
更特別的是，杭丁頓蛋白似乎活化了負(fù)責(zé)制造BDNF基因的開關(guān)（稱爲(wèi)啓動(dòng)子）。
We also observed a link between huntingtin and BDNF in experiments involving mice genetically engineered by Michael R.
我們使用加拿大卑詩(shī)大學(xué)的海登等人以基因工程改造的小鼠進(jìn)行實(shí)騐，也可見及杭丁頓蛋白與BDNF之間的關(guān)聯(lián)。
This observation suggests that the absence of normal huntingtin and the presence of mutant huntingtin might be different sides of the same coin.
這項(xiàng)發(fā)現(xiàn)顯示，缺少正常杭丁頓蛋白與表現(xiàn)變異杭丁頓蛋白這兩廻事，很可能是一躰的兩麪。